Edward begged doctors to have his "demon head" removed, because, supposedly, it whispered horrible things to him at night, but no doctor would attempt it.He committed suicide at the age of 23.
You may think this is just a creepypasta. It is true.
Source: Edward Mordrake
From the very site linked on this ‘true story’:
“It is difficult to establish the facts behind Edward Mordake's condition due to the lack of reliable medical records. Not even his date of birth and death are recorded and there are conflicting accounts regarding his suicide, as well as placement and position of his extra face. Much of what is known is based on oral retelling.”